Malignant multiple sclerosis: clinical and demographic prognostic factors.
نویسندگان
چکیده
Patients with malignant multiple sclerosis (MMS) reach a significant level of disability within a short period of time (Expanded Disability Status Scale score of 6 within five years). The clinical profile and progression of the disease were analyzed in a Brazilian cohort of 293 patients. Twenty-five (8,53%) patients were found to have MMS and were compared with the remaining 268 (91,47%). Women, non-white patients, older age at disease onset, shorter intervals between the first attacks, and more attacks in the first two years of the disease were all more common in the MMS group. These findings could serve as prognostic factors when making therapeutic decisions.
منابع مشابه
The relationship of psychological factors, demographic features and disease characteristics with self-management of multiple sclerosis patients
Introduction: Self-management is an important act of controlling the adverse outcomes in multiple sclerosis as a chronic and debilitating disease. This study was aimed to consider the relationship of psychological factors, demographic features and disease characteristics with self-management behaviors and predicting it among patients with multiple sclerosis. Methods: In the correlational stu...
متن کاملDefining high, medium and low impact prognostic factors for developing multiple sclerosis.
Natural history studies have identified factors that predict evolution to multiple sclerosis or risk of disability accumulation over time. Although these studies are based on large multicentre cohorts with long follow-ups, they have limitations such as lack of standardized protocols, a retrospective data collection or lack of a systematic magnetic resonance imaging acquisition and analysis prot...
متن کاملClinical and demographic predictors of long-term disability in patients with relapsing-remitting multiple sclerosis: a systematic review.
OBJECTIVE To identify clinical and demographic factors associated with long-term disability in patients with relapsing-remitting multiple sclerosis. DATA SOURCES We searched the MEDLINE (1966-May 2005), EMBASE, CINAHL, Cochrane, and PsycINFO computerized databases, and reviewed reference lists of retrieved articles. STUDY SELECTION We included studies that examined predictors of long-term d...
متن کاملThe Factors Associated With Olfactory Dysfunction in Patients with Multiple Sclerosis
Introduction: An impaired sense of smell has a remarkable impact on the quality of life. It is seen in a variety of neurodegenerative diseases such as Parkinson disease. In this study, we assessed the olfactory function in patients with Multiple Sclerosis (MS) by Sniff Magnitude Test (SMT). Methods: A cross-sectional study was conducted on 48 patients with MS. A questionnaire, including demog...
متن کاملپارامترهای بالینی، روانشناختی و جمعیتشناختی درد بدنی در مولتیپل اسکلروزیس
Background: Body pain in multiple sclerosis (MS) is a common phenomenon that can create or exacerbate by different parameters of clinical, psychological and demographic. The aim of this study was to investigate the relationship between parameters of clinical (fatigue, clinical course, body mass index and duration), psychological (depression, anxiety and stress) and demographic (age, gender, mar...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
- Arquivos de neuro-psiquiatria
دوره 75 3 شماره
صفحات -
تاریخ انتشار 2017